Professor Struther Arnott

CBE PhD DSc ScD LLD FKC FRS,

Cancer Research UK BioMolecular Structure Group,
School of Pharmacy, University of London,
29-39 Brunswick Square,
London WC1N 1AX,
United Kingdom

Telephone: (+44) (0) 792 962 9769;
E-mail: struther.arnott@pharmacy.ac.uk

For more information see curriculum vitae of Struther Arnott

Research Interests are focused on the ordered secondary structures of linear biopolymers and methods of determining their structures mainly by X-ray diffraction analysis of oriented fibres that are sometimes also polycrystalline and by molecular modelling. Rationalizing the exploitation of such structures by biological systems, in the food and other industries, and in medicine is the main consequential activity. The molecular systems studied are mostly polynucleotides and the gel-forming polysaccharides of plant and animal connective tissues but interesting polypeptides (collagen) and polyisoprenes (rubber) have also received attention.

A Selection of Publications illustrates our interests:

  • Ganeshalingam, R., J. M. Squire and S. Arnott. 2006. A new structure for crystalline natural rubber. Macromolecules 39(20):7004-7014.
  • Arnott, S. 2006. DNA polymorphism and the early history of the double helix. Trends in the Biochemical Sciences 31:349-354.
  • Arnott, S. 2000. Lessons for today and tomorrow from yesterday: the structure of alginate gels. Fiber Diffraction Review 9:44-51.
  • Arnott, S. 1999. Polynucleotide secondary structures: an historical perspective. (Nucleic Acid Structure, Stephen Neidle, ed. Oxford University Press) pp. 1-38.
  • Chandrasekaran, R. and S. Arnott. 1989. The structures of DNA and RNA helices in oriented fibers. In Landolt Bornstein Numerical Data and Functional Relationships in Science And Technology, Vol. VII/Ib (Ed. W. Saenger, Springer-Verlag), pp 31-170
  • Arnott, S., R. Chandrasekaran, R. P. Millane and H.-S. Park. 1986. DNA-RNA hybrid secondary structures. J. Mol. Biol. 188:631-640.
  • Arnott, S., R. Chandrasekaran, L. C. Puigjaner, J. K. Walker, I. H. Hall, D. L. Birdsall and R. L. Ratliff. 1983. Wrinkled DNA. Nucleic Acids Res. 11: 1457-1474.
  • Arnott, S., A. K. Mitra and S, Raghunathan. 1983. The hyaluronic acid double helix. J. Mol. Biol. 169:861-872.
  • Leslie, A.G.W., S. Arnott, R. Chandrasekaran and R. L. Ratliff. 1980. Polymorphism of DNA double helices. J. Mol. Biol. 143:49-72.
  • Arnott, S., R. Chandrasekaran, D. L. Birdsall, A.G.W. Leslie and R. L. Ratliff. 1980. Left-handed DNA helices. Nature 283:743-745.
  • Arnott, S., W. E. Scott, D. A. Rees and C.G.A. McNab. 1974. iota-Carrageenan: Molecular structure and packing of polysaccharide double helices in oriented fibres of divalent cation salts. J. Mol. Biol. 90:253-267.
  • Arnott, S., W. Fuller, A. Hodgson and I. Prutton. 1968. Molecular conformations and structural transitions of RNA complementary helices and their possible biological significance. Nature 220:561-564.
  • Arnott, S., M.H.F. Wilkins, W. Fuller and R. Langridge. 1967. Molecular and crystal structures of double-helical RNA. J. Mol. Biol. 27:525-533.
  • Arnott, S. and A. J. Wonacott. 1966. Atomic co-ordinates for an alpha-helix: refinement of the crystal structure of alpha-poly-L-alanine. J. Mol. Biol. 21:371-383.
  • Arnott, S., F. Hutchinson, M. Spencer, M.H.F. Wilkins, W. Fuller and R. Langridge. 1966. X-ray diffraction studies of double helical RNA. Nature 211:227-232.




Our work is supported by Cancer Research UK , The Association for International Cancer Research , The European Union and BBSRC.
We are based at The School of Pharmacy
Copyright © 2008 Cancer Research UK Biomolecular Structure Group