|
|
|
|
|
|
 |
|
|
Moorhouse AD, Santos AM, Gunaratnam M, Moore M, Neidle S, Moses JE.
Stabilization of G-quadruplex DNA by highly selective ligands via click chemistry.
J Am Chem Soc. 2006 Dec 20;128(50):15972-3. No abstract available.
|
|
Redman JE, Ladame S, Reszka AP, Neidle S, Balasubramanian S.
Discovery of G-quadruplex stabilizing ligands through direct ELISA of a one-bead-one-compound library.
Org Biomol Chem. 2006 Dec 7;4(23):4364-9. Epub 2006 Oct 24.
|
|
Moore MJ, Cuenca F, Searcey M, Neidle S.
Synthesis of distamycin A polyamides targeting G-quadruplex DNA.
Org Biomol Chem. 2006 Sep 21;4(18):3479-88. Epub 2006 Aug 14.
|
|
Burge S, Parkinson GN, Hazel P, Todd AK, Neidle S.
Quadruplex DNA: sequence, topology and structure.
Nucleic Acids Res. 2006;34(19):5402-15. Epub 2006 Sep 29. Review.
|
|
White EW, Tanious F, Ismail MA, Reszka AP, Neidle S, Boykin DW, Wilson WD.
Structure-specific recognition of quadruplex DNA by organic cations: Influence of shape, substituents and charge.
Biophys Chem 2006 Jun 20; [Epub ahead of print]
|
|
Evans DA, Neidle S.
Virtual screening of DNA minor groove binders.
J Med Chem 49(14): 4232-4238, 2006.
|
|
Fernando H, Reszka AP, Huppert J, Ladame S, Rankin S, Venkitaraman AR, Neidle S, Balasubramanian S.
A Conserved Quadruplex Motif Located in a Transcription Activation Site of the Human c-kit Oncogene.
Biochemistry 45(25): 7854-7860, 2006.
|
|
Reed JE, Arnal AA, Neidle S, Vilar R.
Stabilization of G-Quadruplex DNA and Inhibition of Telomerase Activity by Square-Planar Nickel(II) Complexes.
J Am Chem Soc 128(18): 5992-5993, 2006.
|
|
Hazel P, Parkinson GN, Neidle S.
Predictive modelling of topology and loop variations in dimeric DNA quadruplex structures.
Nucleic Acids Res 34(7): 2117-2127, 2006.
|
|
Hazel P, Parkinson GN, Neidle S.
Topology variation and loop structural homology in crystal and simulated structures of a bimolecular DNA quadruplex.
J Am Chem Soc 128(16): 5480-5487, 2006.
|
|
Le Sann C, Baron A, Mann J, van den Berg H, Gunaratnam M, Neidle S.
New mustard-linked 2-aryl-bis-benzimidazoles with anti-proliferative activity.
Org Biomol Chem 4(7): 1305-1312, 2006.
|
|
Franceschin M, Rossetti L, D'Ambrosio A, Schirripa S, Bianco A, Ortaggi G, Savino M, Schultes C, Neidle S.
Natural and synthetic G-quadruplex interactive berberine derivatives.
Bioorg Med Chem Lett 16(6): 1707-1711, 2006.
|
|
Ladame S, Schouten JA, Roldan J, Redman JE, Neidle S, Balasubramanian S.
Exploring the recognition of quadruplex DNA by an engineered cys(2)-his(2) zinc finger protein.
Biochemistry 45(5): 1393-1399, 2006.
|
|
Moore MJ, Schultes CM, Cuesta J, Cuenca F, Gunaratnam M, Tanious FA, Wilson WD, Neidle S.
Trisubstituted Acridines as G-quadruplex Telomere Targeting Agents. Effects of Extensions of the 3,6- and 9-Side Chains on Quadruplex Binding, Telomerase Activity, and Cell Proliferation.
J Med Chem 49(2): 582-599, 2006.
|
|
Campbell NH, Evans DA, Lee MP, Parkinson GN, Neidle S.
Targeting the DNA minor groove with fused ring dicationic compounds: comparison of in silico screening and a high-resolution crystal structure.
Bioorg Med Chem Lett 16(1): 15-19, 2006.
|
|
|
|